Generics:Amlexanox 5%
Apsol 5 gm Oral Paste is shown for the treatment of aphthous ulcers in individuals with the typical resistant framework.
The component of activity by which Amlexanox quickens mending of aphthous ulcers is obscure. In vitro considers have illustrated Amlexanox to be a strong inhibitor of the arrangement and discharge of fiery go-betweens (histamine and leukotrienes) from pole cells, neutrophils, and mononuclear cells. Given orally to creatures, Amlexanox has illustrated anti-allergic and anti-inflammatory exercises and has been appeared to stifle both prompt and postponed sort touchiness responses. The significance of these exercises of Amlexanox to its impacts on aphthous ulcers has not been established.
Adults (over 18 years of age): Apply the paste as soon as possible after noticing the symptoms of an aphthous ulcer. Continue to use the paste four times daily, preferably following oral hygiene after breakfast, lunch, dinner, and at bedtime. Dry the ulcer(s) by gently patting it with a soft, clean cloth. Wash hands before applying. Moisten the tip of the index finger & squeeze a dab of paste approximately ¼ inch (0.5 cm) onto the fingertip. Gently dab the paste onto each ulcer. Repeat the process if more than one ulcer are present. Wash hands after application. Use the paste until the ulcer heals. If significant healing or pain relief has not occurred in 10 days, consultation with the physician is required.
Antidepressants such as SSRIs and related antidepressants should not be started for at least two weeks after stopping an MAOI. An MAOI, on the other hand, should not be started until at least one week after an SSRI or similar antidepressant has been discontinued (2 weeks in the case of paroxetine and sertraline, at least 5 weeks in the case of fluoxetine).
Amlexanox verbal glue is contraindicated in patients with known extreme touchiness to Amlexanox or other fixings within the detailing.
The most common side effects are transient pain, stinging, and/or burning at the site of application. The less frequent side effects are contact mucositis, nausea, and diarrhea.
Pregnancy category B. No adverse fetal effects were observed during teratological studies on animals, but there are no adequate and well-controlled studies in pregnant women. So this drug should be used during pregnancy only if clearly needed.
Lactation: Amlexanox was found in the milk of lactating rats; therefore, caution should be exercised when administering Amlexanox oral paste to a nursing woman.
Wash hands quickly after applying Amlexanox verbal glue specifically to ulcers with the fingertips. Wash eyes expeditiously in the event that they ought to come in contact with the glue. Within the occasion that a hasty or contact mucositis happens, cease to utilize.
Drugs for Aphthous ulcer
Protect from light and moisture by storing below 30°C. Keep the medicine out of children's reach.
Apsol 5
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