Beuflox 60 mlPowder for Suspension

Indications of Beuflox 60 ml Powder for Suspension

Ciprofloxacin is indicated for the treatment of the following infections caused by sensitive bacteria:

• Severe systemic infections: e.g; septicemia, bacteremia, peritonitis, infections in immunosuppressed patients with haematological or solid tumors and in patients in intensive care unitwith specific problems such as infected burns.
• Respiratory tract infections: Lobar and broncho pneumonia, acute and chronic bronchitis and empyema.
• Urinary tract infections: Uncomplicated and complicated urethritis, cystitis, pyelonephritis, prostatitis and epididymitis.
• Skin and soft tissue infections: Infected ulcers, wound infections, abscesses, cellulitis, otitis externa, erysipelas and infected burns.
• Gastrointestinal infections: Enteric fever, infective diarrhea.
• Infections of the biliary tract: Cholangitis, cholecystitis, empyema of the gall bladder.
• Intra-abdominal infections: Peritonitis, intra abdominal abscesses.
• Bone and joint infections: Osteomyelitis, septic arthritis.
• Pelvic infections: Salpingitis, endometritis, pelvic inflammatory diseases.
• Eye, ear, nose and throat infections: Otitis media, sinusitis, mastoiditis, tonsillitis.
• Gonorrhoea: Urethral, rectal and pharyngeal gonorrhoea caused by beta-lactamase producing organism or organisms moderately sensitive to penicillin.

Pharmacology of Beuflox 60 ml Powder for Suspension

Ciprofloxacin may be a manufactured fluoroquinolone. It has bactericidal movement against a wide run of gram-positive and gram-negative living beings. It represses bacterial DNA blend by authoritative with the bacterial enzyme-DNA gyrase and topoisomerase IV which are mindful for DNA supercoiling.

Dosage & Administration of Beuflox 60 ml Powder for Suspension

Adult :

use in conjunction with metronidazole

Children and adolescents:

RTI & GI infections: Neonate-15mg/kg twice daily, Child (1 month -18 years)-20mg/kg (max 750 mg) twice daily;

UTI: Neonate-10 mg/kg twice daily, Child (1 month -18 years)-10mg/kg (max 750 mg) twice daily;

Pseudomonal lower respiratory tract infection in cystic fibrosis: Child (1 month -18 years) - 20mg/kg (max 750 mg) twice daily;

Anthrax (treatment & post exposure prophylaxis): Child (1 month -18 years) - 20mg/kg (max 750 mg) twice daily.

Interaction of Beuflox 60 ml Powder for Suspension

Concurrent organization of Ciprofloxacin ought to be maintained a strategic distance from with Magnesium or Aluminum containing stomach settling agents or sucralfate or with other items containing Calcium, Press or Zinc. These items may be taken two hours after or six hours some time recently Ciprofloxacin. Ciprofloxacin ought to not be taken concurrently with drain or other dairy items, since retention of Ciprofloxacin may be altogether diminished. Dietary calcium could be a portion of a supper, be that as it may, does not altogether influence the assimilation of Ciprofloxacin.

Contraindications

Ciprofloxacin is contraindicated in patients who have hypersensitivity to Ciprofloxacin or other quinolones.

Side Effects of Beuflox 60 ml Powder for Suspension

Ciprofloxacin is generally well tolerated. Frequent adverse reactions are- Gastrointestinal disturbance: e.g. nausea diarrhea, vomiting, dyspepsia, abdominal pain. Disturbance of the CNS: e.g. dizziness, headache, tiredness, confusion, convulsions. Hypersensitivity reactions: e.g. skin rashes, pruritus, and possible systemic reactions. Other possible side effects are - joint pain, light sensitivity, transient increase in liver enzyme (especially in patients with history of liver damage), serum bilirubin, urea or serum creatinine. Arthralgia and myalgia may also occur.

Pregnancy & Lactation

Reproduction studies performed in rats and rabbits using parenteral and oral administration did not reveal any evidence of teratogenicity, impairment of fertility or impairment of pre or postnatal development. However, as with other quinolones, Ciprofloxacin has been shown to cause arthropathy in immature animals and therefore, its use during pregnancy is not recommended. Studies in rats have indicated that Ciprofloxacin is secreted in milk, administration to nursing mothers is thus not recommended.

Precautions & Warnings

Ciprofloxacin should be used with caution in patients with a history of convulsive disorders. Crystalluria related to the use of Ciprofloxacin has been observed only rarely. Patients receiving Ciprofloxacin should be well hydrated to avoid excessive alkalinity of the urine.

Therapeutic Class

4-Quinolone preparations, Anti-diarrhoeal Antimicrobial drugs

Storage Conditions

Keep below 30°C temperature, secured from light & dampness. Keep out of the reach of children.

Pharmaceutical Name of Beuflox 60 ml Powder for Suspension

Incepta Pharmaceuticals Ltd

Generic of Beuflox 60 ml Powder for Suspension

Ciprofloxacin