Cinagen-DOphthalmic Solution

Generic

Indications

Moxifloxacin and Dexamethasone eye drops are used to treat infections caused by susceptible microorganisms in the eyes, as well as to avoid inflammation and bacterial infection following eye surgery.

Pharmacology

This eye drop contains Moxifloxacin, a fourth-generation fluoroquinolone, and Dexmethasone, a powerful corticosteroid. By inhibiting DNA gyrase and Topoisomerase IV, moxifloxacin prevents infection. By decreasing the release of inflammatory mediators, dexamethasone effectively reduces inflammation.

Dosage & Administration

In the prevention of infection and post-surgical ocular inflammation: Instill 1 drop, 4 times a day, in the eye to be operated, from 1 day before surgery until 15 days after surgery.

In patients undergoing cataract surgery: The day of surgery instill the medication immediately after eye surgery.

In patients undergoing LASIK refractive surgery: On the day of surgery instill the medication at least 15 minutes after ocular surgery.

In eye infections caused by susceptible microorganisms: Instill 1 drop, 4 times a day, for up to 7 days.

Contraindications

Quinolone hypersensitivity. Vaccinia, varicella, and other viral illnesses of the cornea and conjunctiva. Epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, varicella, and other viral disorders of the cornea and conjunctiva. An eye infection caused by mycobacteria. Infections of the ocular structures caused by fungi. Glaucoma and illnesses that cause corneal or sclera thinning.

Side Effects

Conjunctivitis, dry eye, keratitis, ocular discomfort, hyperemia, pain, subconjunctival hemorrhage, and tears are all side effects of moxifloxacin.

Visual acuity and field abnormalities, cataract development, subsequent ocular infection following inhibition of the host response, and globe perforation are among side effects of dexamethasone.

Pregnancy & Lactation

In pregnant women, there are no appropriate and well-controlled trials. Only use Moxifloxacin and Dexamethasone eye drops during pregnancy if the possible benefit outweighs the potential danger to the baby. When using a combination of Moxifloxacin and Dexamethasone eye drops on a breastfeeding woman, use caution.

Precautions & Warnings

Only for ophthalmic use. The solution should not be injected directly into the anterior chamber of the eye or under the conjunctiva. Steroid usage for a long time might cause ocular hypertension.

Therapeutic Class

Storage Conditions

Keep it cool, below 30°C, and out of direct sunlight. The contents of the container must be consumed within 28 days of opening, and they can be stored at room temperature up to 30°C. After 28 days, toss it out. Keep out of children's reach.

Pharmaceutical Name

Navana Pharmaceuticals Ltd.