Cipcin 5 mlOphthalmic Solution

Indications of Cipcin 5 ml Ophthalmic Solution

Ciprofloxacin 0.3% Eye/Ear Drops is indicated for the treatment of infections caused by susceptible strains of the designated microorganisms in the conditions listed below:

• Corneal Ulcers: Pseudomonas aeruginosa, Serratia marcescens, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae.
• Bacterial Conjunctivitis: Haemophilus influenzae, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae. It is also indicated in the treatment of keratitis, kerato-conjunctivitis, blepharitis, blepharo-conjunctivitis, dacryocistitis, prophylaxis of ocular infections due to Neisseria gonorrhea or Chlamydia trachomatis, prevention of ocular infections after removal of a corneal or physical agent before or after ocular surgery.
• Ear: Otitis externa, acute otitis media, chronic suppurative otitis media. Prophylaxis in otic surgeries such as mastoid surgery.

Pharmacology of Cipcin 5 ml Ophthalmic Solution

Ciprofloxacin is a broad-spectrum antibacterial drug that is administered intravenously. Ciprofloxacin's bactericidal effect is due to suppression of the topoisomerase II (DNA gyrase) and topoisomerase IV enzymes, which are essential for bacterial DNA replication, transcription, repair, and recombination.

Dosage & Administration of Cipcin 5 ml Ophthalmic Solution

Corneal ulcers: The recommended dosage regimen for the treatment of corneal ulcers is two drops into the affected eye every 15 minutes for the first 6 hours and then two drops into the affected eye every 30 minutes for the remainder of the first day. On the second day, instill 2 drops in the affected eye hourly. On the third through the fourteenth day, place two drops in the affected eye every four hours. Treatment may be continued after 14 days if corneal re-epithelization has not been occurred.

Bacterial conjunctivitis: The recommended dosage regimen for the treatment of bacterial conjunctivitis is one or two drops instilled into the conjunctival sac(s) every two hours while awake for two days and one or two drops every four hours while awake for the next five days.

Ear infections: For all infections, 2-3 drops every 2-3 hours initially, reducing the frequency of the instillation with control of infection. Treatment should be continued at least 7 days.

Interaction of Cipcin 5 ml Ophthalmic Solution

With ophthalmic Ciprofloxacin, no specific medication interaction studies have been found.

Contraindications

Hypersensitivity to the quinolone antibacterial group or any of the formulation's components.

Side Effects of Cipcin 5 ml Ophthalmic Solution

Following administration, you may experience local burning or pain, itching, a foreign body sensation, crystalline precipitates, lid border crusting, conjunctival hyperemia, and a foul taste. It's possible that you'll have photophobia and nausea.

Pregnancy & Lactation

If the possible advantages outweigh the potential danger during pregnancy, don't use it. It is unknown if topical ophthalmic administration causes excretion in human milk. Nursing moms should be treated with caution.

Precautions & Warnings

Ciprofloxacin usage in the eyes for a long time might cause non-susceptible organisms, such as fungus, to overgrow. Ciprofloxacin should be stopped as soon as a skin rash or other symptom of hypersensitivity response appears.

Therapeutic Class

Aural Anti-bacterial preparations, Ophthalmic antibacterial drugs

Storage Conditions

Store below 30° C in a cool and dry place protected from light. Keep out of reach of children. Do not touch the dropper tip to surfaces since this may contaminate the solution. Do not use after 30 days of first opening.

Pharmaceutical Name of Cipcin 5 ml Ophthalmic Solution

Biopharma Laboratories Ltd

Generic of Cipcin 5 ml Ophthalmic Solution

Ciprofloxacin