Citicol 500Tablet

Indications of Citicol 500 Tablet

Citicoline Sodium is used to treat cerebrovascular disorders, such as ischemia from a stroke, by speeding up the recovery of consciousness and overcoming motor deficits. Patients with moderate to severe stroke who receive treatment within the first 24 hours after onset had a better chance of recovering completely in three months.

• Head trauma or brain injury causes cerebral insufficiency (e.g. dizziness, memory loss, poor attention, and disorientation).
• Degenerative disease (Alzheimer's disease) causes cognitive impairment.
• Parkinson's disease: Citicoline has been demonstrated to be an effective Parkinson's disease co-therapy.

Pharmacology of Citicol 500 Tablet

Citicoline may be a normally occurring substance that's an fundamental middle within the blend of auxiliary phospholipids of cell layer. Verbal measurements of Citicoline is metabolized to choline & cytidine. These at that point enter into the systemic circulation, cross the blood-brain boundary and recombine to create Citicoline inside the central anxious framework. Citicoline actuates the biosynthesis of auxiliary phospholipids within the neuronal layer, advances quick repair of harmed cell surface & mitochondrial film & increments the level of different neurotransmitters like acetylcholine & dopamine. Citicoline has neuroprotective impacts in circumstances of hypoxia & ischemia, as well as made strides learning & memory execution in creature models for the maturing brain. Citicoline restrains the enactment of Phospholipase A2 to avoid apoptotic & necrotic cell death.

Dosage & Administration of Citicol 500 Tablet

Oral:

• Immediate treatment of stroke due to a clot (ischemic stroke): 500-2000 mg of Citicoline per day, start within 24 hours of stroke.
• For decline in thinking skills due to stroke: 1000-2000 mg of Citicoline per day.
• Chronic cerebrovascular disease: 1000 mg daily in divided dose with or between meals for ongoing disease of the blood vessels that serve the brain.

Injection:

• 1 to 2 injections daily.
• Adjust dosage according to the severity.
• Can be administered through intramuscular (IM), or intravenous (IV) [ 3 to 5 minutes] route.

Interaction of Citicol 500 Tablet

Levodopa, carbidopa, and entacapone may be enhanced by citicoline. Citicoline should not be used in conjunction with meclophenoxate-containing products.

Contraindications

Levodopa, carbidopa, and entacapone may be enhanced by citicoline. Citicoline should not be used in conjunction with meclophenoxate-containing products.

Side Effects of Citicol 500 Tablet

Patients having a parasympathetic nervous system that is hypertonic.

Pregnancy & Lactation

Citicoline can have a parasympathetic system stimulating impact as well as a brief and discrete hypotensive effect.

Precautions & Warnings

In the case of persistent cerebral hemorrhage, a daily dose of Citicoline of 1000 mg is indicated.

Therapeutic Class

Stimulant medicines for the central nervous system.

Storage Conditions

Keep the temperature below 30°C and away from light and moisture. Keep out of children's reach.

Pharmaceutical Name of Citicol 500 Tablet

Beximco Pharmaceuticals Ltd

Generic of Citicol 500 Tablet

Citicoline Sodium